YL-109 from Cayman Chemical

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Cayman Chemical for
YL-109

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Description

An anticancer agent; inhibits the proliferation of MCF-7 and MDA-MB-231 cells (IC50s = 0.0858 and 4.2 µM, respectively), as well as migration and invasion by MDA-MB-231 cells in vitro; induces expression of CHIP in MDA-MB-231 cells in an AHR-dependent manner; inhibits MDA-MB-231-derived CSC mammosphere formation at 1 µM; reduces tumor volume and the number of metastases in an MDA-MB-231 mouse xenograft model at 15 mg/kg